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Prevention and Control of Seasonal Influenza with Vaccines, 2020-21

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Summary

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This report updates the 2019\u201320 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines in the United States (MMWR Recomm Rep 2019;68[No. RR-3]).

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Routine annual influenza vaccination is recommended for all persons aged ?6 months who do not have contraindications. A licensed, recommended, and age-appropriate vaccine should be used. Inactivated influenza vaccines (IIVs), recombinant influenza vaccine (RIV), and live attenuated influenza vaccine (LAIV) are expected to be available for the 2020\u201321 season. Standard-dose, unadjuvanted, inactivated influenza (IIV4s), High-dose (HD-IIV4), and adjuvanted (aIIV4) vaccines will be available in quadrivalent formulations. Adjuvanted inactivated influenza vaccine will also be available in a trivalent formulation (aIIV3) . Recombinant (RIV4), cell-culture based (ccIIV4), and live attenuated influenza vaccine (LAIV4) will be available in quadrivalent formulations.

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Updates to the recommendations described in this report reflect discussions during public meetings of ACIP held on October 23, 2019; February 26, 2020; and June 24, 2020.

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Primary updates in this report include the following two items.

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  • First, \n
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    • The egg-based H1N1 vaccine component was updated from an A/Brisbane/02/2018 (H1N1)pdm09-like virus to an A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus.
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    • The cell- or recombinant-based H1N1 vaccine component was updated from an A/Brisbane/02/2018 (H1N1)pdm09-like virus to an A/Hawaii/70/2019 (H1N1)pdm09-like virus.
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    • The egg-based H3N2 vaccine component was updated from an A/Kansas/14/2017 (H3N2)-like virus to an A/Hong Kong/2671/2019 (H3N2)-like virus.
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    • The cell- or recombinant-based H3N2 vaccine component was updated from an A/Kansas/14/2017 (H3N2)-like virus to an A/Hong Kong/45/2019 (H3N2)-like virus.
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    • The B/Victoria lineage vaccine component was updated from a B/Colorado/06/2017 (B/Victoria lineage)-like virus to a B/Washington/02/2019 (B/Victoria lineage)-like virus.
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  • Second, high-dose vaccine and adjuvanted vaccine will be available in quadrivalent formulations (HD-IIV4 and aIIV4) this year. High-dose vaccine will not be available in trivalent formulation.
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This report focuses on the recommendations for use of vaccines for the prevention and control of influenza during the 2020\u201321 season in the United States.

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A Background Document containing further information and a brief summary of these recommendations is available: Influenza ACIP Vaccine Recommendations.

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See Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices \u2014 United States, 2020\u201321 Influenza Season for the full recommendations.

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\n Background \n
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\n Vaccine Composition and Available Products \n
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\n Immunogenicity, Efficacy, and Effectiveness \n
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\n Safety of Influenza Vaccines \n
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\n Links to Current and Past Guidance \n
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Syndicated Content Details:
Source URL: http://www.cdc.gov/flu/professionals/acip/index.htm
Source Agency: Centers for Disease Control and Prevention (CDC)
Captured Date: 2012-06-27 17:11:12.0
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