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Vasculitis - Treatment - Treatment

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Treatment for vasculitis will depend on the type of vasculitis you have, which organs are affected, and the severity of the condition. The goal of treatment is to reduce inflammation. People who have mild vasculitis may find relief with over-the-counter pain medicines. For severe vasculitis, your doctor may prescribe medicines. Surgery to treat vasculitis is rare.

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\n Medicines \n
- Vasculitis - Treatment

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Some of the medicines your doctor may prescribe for vasculitis include:

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  • Corticosteroids to reduce inflammation in your blood vessels. For some types of vasculitis, you will need steroids for months or years. Corticosteroids can affect your bone density and raise your blood sugar and blood pressure levels. Learn about other side effects and risks of corticosteroids.
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  • Dual endothelin receptor antagonists to block the action of a chemical called endothelin that can reduce blood flow.
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  • Immunomodulators, such as colchicine, to reduce the inflammation that causes symptoms. Possible side effects can include gastrointestinal problems.
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  • Immunosuppressive medicines, such as cyclosporine and Mycophenolate mofetil, to suppress or weaken the immune system. Possible side effects of immunosuppressive medicines include an increased risk of infection and birth defects.
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  • Interferon therapy to help block and reduce inflammation. Interferons are molecules that the immune system normally makes, but they have also been developed as medicines.
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  • Interleukin antagonists to reduce inflammation by blocking a protein in the body that triggers inflammation.
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  • Intravenous immunoglobulin (IVIG) to help control the body\u2019s immune and inflammatory response. This medicine also fights infection by introducing purified antibodies from healthy donors into a recipient\u2019s bloodstream. Some people may have a strong negative immune response to IVIG.
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  • Monoclonal antibodies to help suppress the immune system. Possible side effects include fever-like symptoms, stomach pain, and allergic reactions.
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  • Non-steroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation in the body. Over-the-counter NSAIDs such as aspirin, ibuprofen, or naproxen may relieve pain for people who have mild vasculitis. One possible side effect is increased bleeding.
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  • Phosphodiesterase inhibitors to increase blood flow by blocking the action of a particular enzymes in the body. Possible side effects include headaches, heart palpitations, upset stomach, nausea, and vomiting.
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  • Tumor necrosis factor inhibitors to help suppress the immune system by blocking a protein called tumor necrosis factor alpha.
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\n Procedures \n
- Vasculitis - Treatment

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If medicines do not work to treat vasculitis, your doctor may recommend plasmapheresis or surgery.

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  • Plasmapheresis to lower plasma antibody levels may sometimes be performed for vasculitis.
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  • Surgical bypass of the blood vessels may help restore blood flow to some areas in Buerger\u2019s disease.
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Syndicated Content Details:
Source URL: https://www.nhlbi.nih.gov/subscribe/4008
Source Agency: National Heart, Lung, and Blood Institute (NHLBI)
Captured Date: 2019-10-21 19:23:00.0
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