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Disseminated Intravascular Coagulation - Causes - Causes

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DIC is caused by another medical condition that makes the body\u2019s normal blood clotting process become overactive. The condition progresses through two stages. In the early stages, overactive clotting leads to blood clots throughout the blood vessels. The clots can reduce or block blood flow, damaging organs.

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As DIC progresses, the overactive clotting uses up platelet and clotting factors, which are protein that help with normal blood clotting. Without these platelets and clotting factors, DIC can cause bleeding just beneath the skin, in the nose or mouth, or deep inside the body.

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Causes of DIC include:

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  • inflammation in response to infection, injury, or an illness
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  • Severe tissue damage, such as from burns or trauma
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  • Clotting factors caused by some cancers or pregnancy complications. Pregnancy complications that produce clotting factors include placental abruption, in which the placenta separates from the uterus, and amniotic fluid embolism, in which amniotic fluid that surrounds the unborn baby enters the mother\u2019s bloodstream.
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To understand DIC, it helps to understand the body\u2019s normal blood clotting process. Learn more about how blood clots form.

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Blood clots form naturally at sites of injury to prevent or control bleeding. When small cuts or breaks occur on the walls of the blood vessels, your body turns on clotting factors. The clotting factor thrombin forms long fibrin protein strands that clump together with platelets to create blood clots that then seal the cuts or breaks. Once bleeding stops, the body begins breaking down the clots as part of the blood vessel healing process.

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- Disseminated Intravascular Coagulation - Causes

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  • Risk Factors will discuss the conditions that increase your risk of DIC.
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  • Treatment will discuss treatments that your doctors may recommend if you are diagnosed with DIC.
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Syndicated Content Details:
Source URL: https://www.nhlbi.nih.gov/subscribe/3709
Source Agency: National Heart, Lung, and Blood Institute (NHLBI)
Captured Date: 2019-10-21 12:25:00.0
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