{"meta":{"status":200,"messages":[],"pagination":{"max":1,"offset":0,"count":1,"total":1,"pageNum":1,"totalPages":1,"sort":null,"currentUrl":"https://api.digitalmedia.hhs.gov/api/v2/resources/media.json?offset=0&max=1&ignoreHiddenMedia=1&format=json&id=18868&newUrlBase=https://www.nhlbi.nih.gov/subscribe/","nextUrl":null,"previousUrl":null}},"results":[{"content":"<body>\n <div class=\"syndicate\"> \n  <div> \n   <div> \n    <div> \n     <h1 autofocus=\"true\"> Circadian Rhythm Disorders - Risk Factors - Risk Factors </h1> \n     <div> \n      <div> \n       <div> \n        <div> \n         <div> \n          <div> \n           <p>You may have a higher risk for circadian rhythm disorders because of internal factors such as your age, your sex, family history and genetics, and certain medical conditions that affect your brain or vision. External factors such as your lifestyle habits, environment, and occupation can also increase your risk.</p> \n          </div> \n         </div> \n        </div> \n       </div> \n       <div data-viewtype=\"general-accordion \" role=\"tablist\"> \n        <h3> \n         <div>\n           Age \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>The rhythm and timing of your sleep-wake cycle can change with age because of changes in your brain. Teens may naturally have a later bedtime than adults, which raises their risk for delayed sleep-wake phase disorder. Older adults, on the other hand, usually sleep and wake up early. This raises their risk for advanced sleep-wake phase disorder. Older adults are also at higher risk for shift work disorder and jet lag disorder.</p> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Environment or occupation \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>People who work during the night have a higher risk for shift work disorder. Jet lag disorder is more common in pilots, flight attendants, athletes, and people who travel often for business.</p> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Family history and genetics \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Your genes may play a role in whether you naturally wake up early in the morning or go to sleep later at night. This genetic preference of an early or late bedtime can raise your risk for advanced or delayed sleep-wake phase disorder if your rhythm is out of sync with your environment or social responsibilities.</p> \n           <p><span><span><a href=\"#glossary-term-modal-84178\" aria-controls=\"glossary-term-modal-84178\" data-open-modal=\"glossary-term-modal-84178\" data-id=\"84178\"> mutations <i aria-hidden=\"true\"></i> </a> <span aria-labelledby=\"glossary-term-modal-84178-heading\" aria-describedby=\"glossary-term-modal-84178-description\"> <span> <span> <span> <span>mutation</span> <button type=\"button\" aria-label=\"Close this window\" data-close-modal> <i></i> </button> </span> <span> <span>(myoo-TAY-shun):</span><br> <span>Any change in a nucleic acid sequence, such as DNA or RNA.</span> </span> </span> </span> </span></span></span> in certain genes can also raise your risk for circadian rhythm disorders. These include the genes that control your body\u2019s <span><span>circadian clocks</span></span> and certain genes that affect brain development or health.</p> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Lifestyle habits \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Lifestyle habits can raise your risk for circadian rhythm disorders. These include:</p> \n           <ul> \n            <li>Alcohol use</li> \n            <li><span><span>Chronic</span></span> caffeine use</li> \n            <li>Frequent air travel</li> \n            <li>Illegal drug use</li> \n            <li>Lack of exposure to natural light during the day</li> \n            <li>Unhealthy sleep habits such as regularly staying up late and nighttime exposure to artificial light, including light from a TV screen, a smartphone, or a very bright alarm clock</li> \n           </ul> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Other medical conditions \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Several medical conditions can increase your risk for circadian rhythm disorders, including:</p> \n           <ul> \n            <li><strong>Autism spectrum disorders</strong></li> \n            <li><strong>Certain genetic conditions,</strong> such as Smith-Magenis syndrome, Angelman syndrome, and Huntington\u2019s disease</li> \n            <li><strong>Conditions that affect eyesight,</strong> such as blindness and macular degeneration. This raises the risk for non-24-hour sleep-wake rhythm disorder.</li> \n            <li><strong>Conditions that cause damage to the brain,</strong> such as traumatic brain injuries, <a href=\"https://www.nhlbi.nih.gov/health-topics/stroke\">strokes</a>, and brain <span><span>tumors</span></span></li> \n            <li><strong>Mental health conditions,</strong> such as bipolar disorder, major depression, obsessive-compulsive disorder, and schizophrenia. This raises the risk of delayed sleep-wake phase disorder.</li> \n            <li><strong><span><span>Neurodegenerative</span></span></strong> <strong>diseases,</strong> such as Alzheimer\u2019s disease, dementia, and Parkinson\u2019s disease. These conditions are more common in older adults and can increase your risk for irregular sleep-wake phase disorder.</li> \n           </ul> \n           <p>How do neurodegenerative conditions lead to circadian rhythm disorders?</p> \n          </div> \n         </div> \n         <div> \n          <div> \n           <a href=\"https://www.nhlbi.nih.gov/subscribe/javascript:void(null)\">Read more</a> \n          </div> \n          <div> \n           <div> \n            <div> \n             <p>Neurodegenerative diseases such as Alzheimer\u2019s disease and dementia can damage brain cells that process light and other signals from the environment. Without correct information, your body makes less melatonin and at different times of the day than expected. This can lead to irregular sleep-wake rhythm disorder or a complete reversal of the normal sleep-wake cycle.</p> \n             <p>People who have neurodegenerative conditions and are living in nursing homes may not have a clear pattern of day and night. They may have few social interactions during the day and be awakened for medicine and care throughout the day and night. This can lead to a disrupted sleep-wake cycle, which may cause circadian rhythm disorders.</p> \n            </div> \n           </div> \n           <div> \n            <a href=\"https://www.nhlbi.nih.gov/subscribe/javascript:void(null)\">Read less</a> \n           </div> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Sex \n         </div> <span> - Circadian Rhythm Disorders - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Men are more likely to have advanced sleep-wake phase disorder than women.</p> \n           <p>Women may be more likely to experience circadian rhythm disorders at certain stages of life.</p> \n           <ul> \n            <li><strong>Hormonal changes</strong> that happen during pregnancy, after childbirth, and at menopause can cause problems with sleep.</li> \n            <li><strong>Discomfort during pregnancy</strong> may also prevent good-quality sleep.</li> \n            <li><strong>After childbirth, sleep interruptions and nighttime exposure</strong> <strong>to light</strong> while caring for a newborn can increase your risk for circadian rhythm disorders.</li> \n           </ul> \n          </div> \n         </div> \n        </div> \n       </div> \n      </div> \n     </div> \n    </div> \n   </div> \n  </div> \n </div>\n <script type=\"application/ld+json\">{\"@context\":\"http://schema.org\",\"@type\":\"Article\",\"headline\":\"Circadian Rhythm Disorders \u2013 Risk Factors\",\"datePublished\":\"2019-40-27T13:40:00Z\",\"description\":\"You may have a higher risk for circadian rhythm disorders because of internal factors such as your age, your sex, family history and genetics, and certain medical conditions that affect your brain or vision. External factors such as your lifestyle habits, environment, and occupation can also increase your risk.\",\"about\":\"prevention, research, policy, cessation, secondhand smoke, Sleep-wake cycle disorders, Quitting Resources, Guidance, Regulations and Compliance, Prevent Smoking and Tobacco Use\",\"audience\":\"\",\"dateCreated\":\"2019-40-27T13:40:00Z\",\"dateModified\":\"2026-00-09T05:00:13Z\",\"sourceOrganization\":\"National Heart, Lung, and Blood Institute\"}</script>\n</body><div class='syndicate'><span><Strong>Syndicated Content Details:</strong></span><br/><span>Source URL: <a href='https://www.nhlbi.nih.gov/subscribe/87589'>https://www.nhlbi.nih.gov/subscribe/87589</a></span><br/><span>Source Agency: <a href='http://www.nhlbi.nih.gov'>National Heart, Lung, and Blood Institute (NHLBI)</a></span><br/><span>Captured Date: 2019-09-27 13:40:00.0</span><br/></div><iframe src=\"//www.googletagmanager.com/ns.html?id=GTM-KT9TM9&mediaId=18868&mediaType=html&sourceUrl=https%3A%2F%2Fwww.nhlbi.nih.gov%2Fsubscribe%2F87589&userId=-1&sourceId=9&sourceAcronym=NHLBI&campaignId=-1&campaignName=null&languageId=1&isoCode=eng\" height=\"0\" width=\"0\" style=\"display:none;visibility:hidden\"></iframe><noscript><iframe src=\"//www.googletagmanager.com/ns.html?id=GTM-KT9TM9&mediaId=18868&mediaType=html&sourceUrl=https%3A%2F%2Fwww.nhlbi.nih.gov%2Fsubscribe%2F87589&userId=-1&sourceId=9&sourceAcronym=NHLBI&campaignId=-1&campaignName=null&languageId=1&isoCode=eng\" height=\"0\" width=\"0\" style=\"display:none;visibility:hidden\"></iframe></noscript>","description":"You may have a higher risk for circadian rhythm disorders because of internal factors such as your age, your sex, family history and genetics, and certain medical conditions that affect your brain or vision. External factors such as your lifestyle habits, environment, and occupation can also increase your risk.","id":18868,"mediaType":"Html","name":"Circadian Rhythm Disorders \u2013 Risk Factors","sourceUrl":"https://www.nhlbi.nih.gov/subscribe/87589"}]}