{"meta":{"status":200,"messages":[],"pagination":{"max":1,"offset":0,"count":1,"total":1,"pageNum":1,"totalPages":1,"sort":null,"currentUrl":"https://api.digitalmedia.hhs.gov/api/v2/resources/media.json?offset=0&max=1&ignoreHiddenMedia=1&format=json&id=18440&newUrlBase=https://www.nhlbi.nih.gov/subscribe/","nextUrl":null,"previousUrl":null}},"results":[{"content":"<body>\n <div class=\"syndicate\"> \n  <div> \n   <div> \n    <div> \n     <h1 autofocus=\"true\"> Pulmonary Hypertension - Risk Factors - Risk Factors </h1> \n     <div> \n      <div> \n       <div> \n        <div> \n         <div> \n          <div> \n           <p>You may have an increased risk for pulmonary hypertension because of your age, environment, family history and <span><span><a href=\"#\" title=\"Definition of genetic \" alt=\"Definition of genetic\" data-term=\"genetic\" data-pronunciation=\"jeh-NEH-tik\" data-definition=\"Having to do with genes. Most genes are sequences of DNA that contain information for making specific proteins or molecules of RNA that perform important functions in a cell. The information in genes is passed from parents to children.\" role=\"link\" data-id=\"83435\"> genetics <i></i></a></span></span>, lifestyle habits, medicines you are taking, other medical conditions, or sex.</p> \n          </div> \n         </div> \n        </div> \n       </div> \n       <div data-viewtype=\"general-accordion \" role=\"tablist\"> \n        <h3> \n         <div>\n           Age \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Your risk of pulmonary hypertension goes up as you get older, although it may occur at any age. The condition is typically diagnosed between ages 30 and 60.</p> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Environment \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>You may be at an increased risk of pulmonary hypertension if you have or are exposed to the following:</p> \n           <ul> \n            <li><strong>Asbestos</strong> or silica</li> \n            <li><strong>Infection</strong> caused by parasites such as schistosomiasis or Echinococcus, which are tapeworms</li> \n           </ul> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Family history and genetics \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Certain genetic disorders, such as Down syndrome, congenital heart disease, and Gaucher disease, can increase your risk of developing pulmonary hypertension.</p> \n           <p>A family history of blood clots or pulmonary embolism also increases your risk of developing pulmonary hypertension.</p> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Lifestyle habits \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Unhealthy lifestyle habits can increase the risk of pulmonary hypertension. These habits include:</p> \n           <ul> \n            <li><strong>Illegal drugs, </strong>such as cocaine and amphetamines<strong> </strong></li> \n            <li><strong>Smoking</strong></li> \n           </ul> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Medicines \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Some medicines may increase your risk of pulmonary hypertension, including:</p> \n           <ul> \n            <li><strong>Chemotherapy medicines</strong> to treat <span><span>cancer</span></span>, such as dasatinib, mitomycin C, and cyclophosphamide</li> \n            <li><strong>Selective serotonin reuptake inhibitors (SSRIs)</strong> to treat depression and anxiety. SSRIs may cause pulmonary arterial hypertension in newborns whose mothers have taken these medicines during pregnancy.</li> \n            <li><strong>Weight-loss drugs</strong> such as fenfluramine and dexfenfluramine, which are no longer approved for weight loss in the United States</li> \n           </ul> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Other medical conditions \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Certain medical conditions may increase your risk of developing pulmonary hypertension:</p> \n           <ul> \n            <li><strong>Blood clotting disorders,</strong> such as <a href=\"https://www.nhlbi.nih.gov/health-topics/venous-thromboembolism\">blood clots in the lungs</a>, a higher-than-normal platelet count in your blood, and conditions that make your blood more likely to clot, such as protein S and C deficiency, <a href=\"https://www.genome.gov/15015167/\" rel=\"noreferrer\">factor V Leiden thrombophilia</a>, antithrombin III deficiency, and <a href=\"https://www.genome.gov/17516396/learning-about-antiphospholipid-syndrome/\" rel=\"noreferrer\">antiphospholipid syndrome</a></li> \n            <li><strong>Chronic kidney disease</strong></li> \n            <li><strong>Diseases that change the structure of the chest wall,</strong> such as scoliosis</li> \n            <li><strong>Infections </strong>such as hepatitis B or C</li> \n            <li><strong>Liver disease </strong>such as cirrhosis</li> \n            <li><strong>Surgical removal of the spleen</strong></li> \n            <li><strong>Thyroid diseases</strong></li> \n           </ul> \n          </div> \n         </div> \n        </div> \n        <h3> \n         <div>\n           Sex \n         </div> <span> - Pulmonary Hypertension - Risk Factors </span> </h3> \n        <div> \n         <div> \n          <div> \n           <p>Pulmonary hypertension is more common in women than in men. Pulmonary hypertension with certain types of heart failure is also more common in women.</p> \n          </div> \n         </div> \n        </div> \n       </div> \n      </div> \n     </div> \n    </div> \n   </div> \n  </div> \n </div>\n <script type=\"application/ld+json\">{\"@context\":\"http://schema.org\",\"@type\":\"Article\",\"headline\":\"Pulmonary Hypertension - Risk Factors\",\"datePublished\":\"2019-32-07T15:32:00Z\",\"description\":\"Your age, environment, family history and genetics, lifestyle habits, medicines you are taking, other medical conditions, and sex can raise your risk of pulmonary hypertension.\",\"about\":\"hypertension, blood pressure, arteries, pulmonary\",\"audience\":\"\",\"dateCreated\":\"2019-32-07T15:32:00Z\",\"dateModified\":\"2026-56-16T01:56:31Z\",\"sourceOrganization\":\"National Heart, Lung, and Blood Institute\"}</script>\n</body><div class='syndicate'><span><Strong>Syndicated Content Details:</strong></span><br/><span>Source URL: <a href='https://www.nhlbi.nih.gov/subscribe/4218'>https://www.nhlbi.nih.gov/subscribe/4218</a></span><br/><span>Source Agency: <a href='http://www.nhlbi.nih.gov'>National Heart, Lung, and Blood Institute (NHLBI)</a></span><br/><span>Captured Date: 2019-01-07 15:32:00.0</span><br/></div><iframe src=\"//www.googletagmanager.com/ns.html?id=GTM-KT9TM9&mediaId=18440&mediaType=html&sourceUrl=https%3A%2F%2Fwww.nhlbi.nih.gov%2Fsubscribe%2F4218&userId=-1&sourceId=9&sourceAcronym=NHLBI&campaignId=-1&campaignName=null&languageId=1&isoCode=eng\" height=\"0\" width=\"0\" style=\"display:none;visibility:hidden\"></iframe><noscript><iframe src=\"//www.googletagmanager.com/ns.html?id=GTM-KT9TM9&mediaId=18440&mediaType=html&sourceUrl=https%3A%2F%2Fwww.nhlbi.nih.gov%2Fsubscribe%2F4218&userId=-1&sourceId=9&sourceAcronym=NHLBI&campaignId=-1&campaignName=null&languageId=1&isoCode=eng\" height=\"0\" width=\"0\" style=\"display:none;visibility:hidden\"></iframe></noscript>","description":"Your age, environment, family history and genetics, lifestyle habits, medicines you are taking, other medical conditions, and sex can raise your risk of pulmonary hypertension.","id":18440,"mediaType":"Html","name":"Pulmonary Hypertension - Risk Factors","sourceUrl":"https://www.nhlbi.nih.gov/subscribe/4218"}]}