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\nWith the growing popularity of gluten-free products at your local grocery store, you may have wondered if you should avoid eating gluten. Sidestepping gluten can be a lifestyle choice for many. But for those with a condition known as celiac disease, it\u2019s a medical necessity.
\nGluten is a protein found in wheat, barley, rye, and sometimes oats\u2014ingredients often used in breads, pastas, and desserts. Some people get gas, diarrhea, or bloating after eating gluten. These symptoms could be caused by intolerance to the protein or a wheat allergy, but celiac disease is different.
\nWhen a person with celiac disease eats or drinks anything with gluten, the body\u2019s immune system attacks the inside of the small intestine. The damage from this attack keeps the body from absorbing needed nutrients. If left untreated, celiac disease can lead to malnutrition, depression, anxiety, anemia, or weakened bones. It can also delay children\u2019s growth.
\nCeliac disease can be hard to spot, because its symptoms can be similar to other disorders. The condition affects about 1% of people worldwide; nearly 80% of them haven\u2019t been diagnosed, says Dr. Alessio Fasano, a celiac disease specialist at Massachusetts General Hospital. \u201cCeliac disease is a clinical chameleon. This creates tremendous confusion and challenging situations for both health care professionals and people who are trying to understand what\u2019s wrong with them,\u201d Fasano says.
\nYour doctor can use a blood test to look for signs of celiac disease. Before the test, continue eating foods with gluten. Otherwise, the results may be negative for celiac disease even if you have it. Eating a regular diet can also help your doctor determine if you have a form of gluten sensitivity that is not celiac disease. Gluten sensitivity is something you may grow out of over time, Fasano explains, whereas celiac disease is a lifelong condition.
\nIf your tests and symptoms suggest celiac disease, your doctor may confirm the diagnosis by removing a small piece of your intestine to inspect it for damage.
\nGenetic tests may be used to detect the genes that turn on the body\u2019s immune response to gluten. Such tests can help rule out celiac disease, but they can\u2019t be used for diagnoses; many people who have the genes never develop celiac disease.
\nFasano\u2019s team is studying why some people with these genes don\u2019t have symptoms. The NIH-funded researchers will follow infants who are at increased risk because a family member has celiac disease. The team hopes its findings will help doctors predict who will get celiac disease and learn how to prevent it.
\nPeople with one autoimmune disease are at increased risk for other autoimmune diseases. Because celiac disease and type 1 diabetes share risk genes, a large international study is following newborns at risk for both conditions to identify environmental factors that may trigger or protect from these diseases.
\nGoing on a strict 100% gluten-free diet for life remains the only treatment for now. \u201cWe can\u2019t take the genes out, so we remove the environmental trigger,\u201d Fasano says.
\nGluten is sometimes found in unexpected sources\u2014such as medications, vitamins, or lip balms\u2014so check ingredient lists carefully. The U.S. Food and Drug Administration has strict regulations for the use of \u201cgluten-free\u201d labels. Talking with a dietitian can also be helpful for learning about your food options.
\nIf you suspect you may have celiac disease, talk with your doctor. Waiting too long for a diagnosis might lead to serious problems.
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